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Human data and transgenic mice have identified many involved proteinases in matrix destruction, including MMP-1, MMP-9, MMP-12, and neutrophil elastase

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For a substance or method to be added to the List, it must be determined that it meets at least two of the following three criteria: It has the potential to enhance or enhances sport performance It represents an actual or potential health risk to athletes It violates the spirit of sport The full 2024 List was published on 28 September 2023, giving more than three months’ notice to athletes, their entourage, and other stakeholders, enabling them to acquaint themselves with any modifications