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π©Ί How Does Diabetes Affect the Kidneys? Over time, persistently high blood sugar can damage the tiny blood vessels in the kidneys, reducing their ability to filter waste effectively. This can lead
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As demonstrated by Sugino et al., estrogen and progesterone withdrawal at the end of the secretory phase may upregulate ROS and downregulate SOD, with the former triggering a sequential cascade that starts by activating nuclear factor kappa-light chain enhancer of activated B cells (NF-ΞΊB) and cyclooxygenase-2 and ends with prostaglandin F 2Ξ± production, culminating in endometrial shedding [17]
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