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As a consequence of this basic fact of biochemistry, one should expect that RNA viruses might exploit various mechanisms to interfere with components of the thioredoxin and glutaredoxin systems, in order to minimize the diversion of ribonucleotides into DNA synthesis

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Nucleotide pyrophosphatase 2, a lipid kinase, has been shown to reduce the generation of ROS and protect cardiomyocytes from erastin-induced ferroptosis (199)