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Therapeutic effects of kefir grain Lactobacillus-derived extracellular vesicles in mice with 2,4,6-trinitrobenzene sulfonic acid-induced inflammatory bowel disease
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Within the IVR domain of Keap1, Cys-273 and Cys-288 are essential for the turnover of Nrf2 in vitro and in vivo , with mutation of either of these residues resulting in the loss of Nrf2 ubiquitination by Keap1 [250, 268]
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