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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI - Nature Communications | Tobias Madl

In addition to IGF-1 and IGF-1R, overexpression of IGF-2 and INSR-A is reported in a wide range of human cancers, including breast, colorectal, prostate, and lung cancers, and is also associated with a poor prognosis [21–23]

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