glutathione reductase enzymatic activity and phenotypes of gsr-1(m+,z-) beauty bundle

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We induced abdominal compartment syndrome (intra-abdominal pressure in thiopental-anesthetized rats at 25 mmHg (60 min), 30 mmHg (30 min), 40 mmHg (30 min), and 50 mmHg (15 min) and in esketamine-anesthetized rats (25 mmHg for 120 min)) as a model of multiple occlusion syndrome

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This approach rationally designs PROTACs to enhance CD36 receptor binding, thereby facilitating transcellular transport and holding promise for improving the bioavailability and in vivo efficacy of bRo5 therapeutics