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801 In mice with I/R injury, methylmalonic acid promotes the expression of NOX2/4, increases ROS production in cardiomyocytes, aggravates myocardial oxidative stress and ferroptosis, and expands myocardial infarction size and cardiac dysfunction

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However, WPC alone had no effect on ROS levels in MDA-MB-231 cells and when administered as part of a combination treatment, it had no effect on the increase in ROS concentration induced by rapamycin 27