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As expected, our combination therapy promoted T cell expansion (Figure 4, A–C) and IFN-γ production (Figure 4, D and E) in vitro and enhanced polyfunctionality (Supplemental Figure 7A) and polyfunctional strength index (Supplemental Figure 7B) of activated CD8 + T cells determined by IsoPlexis single-cell functional proteomics in vitro as compared with single treatment alone
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