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111 Also, TLR5 stimulation of TCM cells isolated from HIV-infected individuals leads to HIV reactivation, although the viability of these cells after stimulation with the TLR5 ligand flagellin was not specifically examined

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302,307 Role of mitochondrial biogenesis in cancer While glycolysis predominates in many tumors, several aggressive cancers—such as melanoma, prostate cancer, and HER2-positive breast cancer—or specific cellular subtypes within tumors show increased levels of PGC1α and enhanced mitochondrial biogenesis to sustain OXPHOS and support metastatic dissemination