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Mohammad Hoesin General Hospital, Sriwijaya University, Palembang, Indonesia 2Department of Biomedical, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia *Corresponding Author: Department of Dermatovenereology, Faculty of Medicine Sriwijaya University, Dr

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Results Gut AstC signaling regulates organismal resistance to nutritional challenges To identify intestinal hormones involved in nutrient sensing and in maintaining energy homeostasis during nutrient stress, we used RNAi to knock down secreted factors in the EECs of the adult Drosophila midgut and tested for changes in organismal starvation resistance (Fig