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Make sure it’s safe for you to approach the person Try to wake them by talking loudly to them and gently shaking their shoulders Check if they're breathing by looking to see if their chest is moving Put them in the recovery position Call 999 for an ambulance, telling emergency services what you know Naloxone If you suspect someone has overdosed, it’s always best to administer naloxone

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Overall, increasing NAD + levels stimulated mitochondrial function, promoting mitophagy and preventing cellular senescence