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Their formation occur in enzymatic or non-enzymatic reactions involving activated chemical species known as "reactive oxygen species" (ROS) which are responsible for toxic effects in the body via various tissue damages
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54, 237–271 10.1146/annurev.bi.54.070185.001321 [DOI] [PubMed] [Google Scholar] 12.Traverso N., Ricciarelli R., Nitti M., Marengo B., Furfaro A.L., Pronzato M.A.et al
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