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Chimeras containing either half of this ABHD5 region (4 1–280/5 277–313/4 318–355 (chimera C) and 4 1–317/5 314–351 (chimera D)), however, were inactive, indicating amino acids within both ABHD5 277–313 and 314–351 are necessary for ATGL activation (Fig

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WASHINGTON — Health advisers met Thursday to review more than a half-dozen peptides, unproven substances that have become a growing wellness trend despite little evidence they are safe or effective