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Oxidative stress influences DNA methylation by activating DNMTs or TETs, and this methylation, in turn, exacerbates oxidative stress (Afanas'ev, 2014
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Nonetheless, the observed lower amount of various tocopherol and tocotrienol isomers in Alzheimer’s patients might suggest that neuroprotection should involve all vitamin E isomers, rather than the action of individual isomers [55]
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