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The proposed model emphasizes that multiple receptors and coreceptors can coalesce into a receptor complex that includes HSPGs, integrins, CyPB, tetraspanin, GFRs, and A2t
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SEPHS2 is the rate-limiting enzyme that converts selenite to selenocysteine, a key substance in the synthesis of many selenium proteins such as glutathione peroxidase, thioredoxin reductase, and formate dehydrogenase [16]
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