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Describing all the evidence is not the scope of this review, which is thus limited on the topic by only presenting some examples and speculations, while proposing that a MMP regulatory loop is the key to underlying bacterial virulence
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In the hippocampus, A β can induce the activation of COX-2 and Bax, and inhibit Bcl-2, cAMP response element binding protein (CREB), BDNF, and TrkB, while naringin can attenuate these effects of A β (Choi et al., 2023)
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