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FD: P app = 41.82 ± 2.50 × 10 −7 cm s −1 , LY: P app = 19.53 ± 1.17 × 10 −6 cm s −1 for the BBB model and the acellular control, respectively), which confirmed the formation of a cellular barrier in the microfluidic platform using the mixed medium (Figs
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Conclusions This review highlights the GCN2–methionine–reactive oxygen species (ROS) axis as an integrated redox-metabolic circuit that plays a central and context-dependent role in shaping T cell anti-tumor immunity
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