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Multifunctional incretin peptides in therapies for type 2 diabetes, obesity and associated co-morbidities - ScienceDirect
It is well established that endocrine ghrelin binds to GhrRs on NPY/AgRP neurons in the ARC, activates them and induces their orexigenic effects, which can lead to increased food intake and adiposity (97–99)
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doi: 10.1111/j.1365-313X.2007.03063.x
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