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Frankly, many current NAD boosting strategies do not fix the root causes of NAD decline (NAMPT and salvage pathway dysfunction, chronic inflammation due to senescence and CD38, excess methylation due to NNMT
AOD-9604 stacks well with other fat loss and recovery tools, but should be used strategically — it’s most effective as a supportive compound rather than the centerpiece of a cycle
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Notably, NNMT inhibition did not impact food intake in the DIO mice nor produce any overt signs of toxicity or adverse behavioral effects at the pharmacologically effective dose
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