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Key findings: A 12-week, randomised, double-blind, placebo-controlled trial in ~300 obese adults tested oral AOD-9604 at various doses Results showed a statistically significant but clinically modest reduction in body weight compared to placebo — approximately 1.6 kg more than placebo over 12 weeks The difference was considered insufficient for regulatory approval as an anti-obesity drug The compound had an excellent safety profile — no serious adverse events attributable to AOD-9604 Phase 2b/3 Trials — Never Completed Following the modest Phase 2 results, Metabolic Pharmaceuticals attempted to advance to larger trials but ultimately discontinued development of AOD-9604 as an oral anti-obesity drug in 2007

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Every time we digest, our stomach acids cause the separation of these vitamins from proteins