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Oxidative stress can lead to alterations in mitochondrial morphology and function, inducing structural changes and functional abnormalities in macromolecules such as proteins, lipids and nucleic acids, ultimately leading to apoptosis and accelerating the progression of diabetic microvascular complications such as diabetic retinopathy ( 4.1 Impaired OXPHOS and recovery in diabetic microvascular complications OXPHOS occurs in mitochondria and is the main process involved in supplying energy for cellular respiration and ATP synthesis (107)

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Chitosan modified metal–organic frameworks as a promising carrier for oral drug delivery