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Although more human studies are needed to validate these results, preclinical studies indicate that it may promote the breakdown of stored fat while having a limited effect on glucose regulation

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The examples include reversible warheads for cysteine such as α-cyanocarbonyls 35 or other α-substituted alkenes with good electron withdrawing groups, 30,36 nitriles, 37 aldehydes, 38 and dihaloacetamides 39 (although the halogens are lost, and the equilibrium is between the free cysteine and 2-oxoacetamide), and thiomethyltetrazines