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In a study by The potential use of curcumin in the MS treatment was suggested by experiments showing that in lipo-polysaccharide-induced human astrocyte cell (U373-MG), the secretion of metalloproteinase (MMP)-9 involved in the enhancement of the BBB permeability, was reduced by curcumin (Seyedzadeh et al., 2014

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Although the role of Nrf2 in these processes is slowly being clarified, the body of literature available on the subject is relatively small, with much remaining to be discovered

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