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However, these conditions are complex and often require a multi-pronged approach that includes strict sun protection, topical depigmenting agents, and potentially other professional treatments

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However, since mtDNA is exclusively maternally inherited, female mitochondria appear to be better equipped to prevent mtDNA damage and mutation to reduce the risk of producing inheritable metabolic disorders (reviewed in Demarest and McCarthy, Mitochondrial dynamics play an important role in maintaining a healthy organelle population (Grimm and Eckert, 2018)

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