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In addition, planar PAH o -quinones produced by human AKR1C enzymes, which are regulated by Nrf2, have been found to bind to the AhR leading to gene activation, thereby demonstrating a level of cross talk involving metabolites generated by Nrf2-regulated genes [234, 235]
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Toxicology in Vitro 2008, 22 (7), 1681–1688
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