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Comprehensive single-cell metabolic profiling identifies targets to sensitize triple-negative breast cancer to chemo-immunotherapy: Cell Reports Medicine
Post-Translational Modifications of GPX4 in Cancer Cells Besides small molecular compounds like FINs, post-translational modifications (PTMs) also provide an emerging perspective to regulate its protein level/activity (Figure 2)
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These differences determine everything from side effect profiles to which patients respond best to each compound
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