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The brains of patients with AD show impaired glucose and oxygen metabolism and impaired activity of pyruvate dehydrogenase, ketoglutarate dehydrogenase, and cytochrome oxidase
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We have shown that the growth of metastatic breast cancer cells in LNs imposes solid stress on HEVs and prevents the infiltration of T cells into the metastatic lesions (56) ( Figure 2 )
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