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TNF-α increases the number of Glu receptors and induces the ingestion of GABA, which in turn reduces the inhibitory drive and induces neuronal excitation, which leads to the development of epilepsy ( Glioma-Associated Epilepsy Glial cells regulate excitatory and inflammatory responses that affect the occurrence of epilepsy (Yamamura et al., 2013)

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[DOI] [PubMed] [Google Scholar] 25.Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, et al