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613 A more recent study identified a bioactive metabolite of sebaleic acid, 6( E ),8( Z )-5-oxo-ODE, which stimulated calcium mobilization in human neutrophils and induced desensitization to 5-oxo-ETE (5-KETE), but not LTB 4 , indicating that this effect was mediated by the oxo-eicosanoid receptor (GPR170)
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