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Finally, in common with other NAD(P) probes, but unlike genetically encoded probes for redox species such as H 2 O 2 6,29,35,49 or glutathione 19 , NAPstars bind their target redox species fully reversibly but do not react with it
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By defining key challenges and future directions, this Review aims to position ferroptosis as a viable therapeutic paradigm and to accelerate progress towards clinical application
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