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(2020) using Hymenobacter latericoloratu CGMCC 16346 to reduce imidacloprid from surface water has shown that the process of the hydroxylation of imidacloprid to 5-hydroxy imidacloprid and olefin imidacloprid was inhibited by the presence of piperonyl butoxide, an inhibitor of cytochrome P450 monooxygenases ( Ensifer adhaerens CGMCC 6315 whose resting cells achieved ∼95% of 200 mg⋅L –1 acetamiprid degradation within 12 h and quickly eliminated ∼88% of 5 mg/kg of residual soil acetamiprid within 2 days (Sun et al., 2018)

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Targeted delivery of probiotics and their metabolites, based on the pathological link between intestinal microbiota metabolites and ferroptosis, may help inhibit ferroptosis, correct microbiota dysregulation, and restore immune homeostasis, offering a promising precision intervention strategy to alleviate IBD inflammation