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In the hinge-latch hypothesis, the conformation of the Nrf2–Keap1 complex is altered upon oxidative stress, implying that induction of target genes is only facilitated by newly synthesized Nrf2
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A TB level of less than 2.4 mg/dL within 1-3 months and less than 1 mg/dL by 12 months can indicate higher chances of native liver survival at those specific time points
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